That's not it dokko - how your eye might perceive grain, even under an optical microscope, how scanners variously do,
and how layers of printing paper emulsion react, are all potentially different. What is your final objective? - if it's a phD thesis on hypotheticals, fine, do it your way. I already know what a gigantic enlargement of a 35 mm image looks like;
it's called a freeway billboard designed for a "normal viewing distance" of a third mile away at 70 mph. No need to convert that into meters and kilometers per hour. It's going to look like mush regardless, grain and all, and nobody cares. But I seldom enlarge anything more than 8X, and I do care.
Besides, if one has precision enlarging equipment, and the will to do so, they can easily achieve optical printing detail finer than the resolution the human eye can detect, even close up. I began by making large Cibachrome images; and that's a medium just like film itself, capable of holding extreme detail. Then I graduated up to even better enlarging lenses, full 8x10 sheet film, along with the advent of even more precise films. The name of the game is neither detail for detail's sake, or big for sake of big, but about all kinds of things factoring into a successful composition which can be appreciated at many levels, including nose-up wearing reading glasses if desired. There's nothing "organically soft" about that. If I want a softer look, there are all kinds of ways to achieve that; but it's not by default.
Over thirty years ago I saw samples of classified photos taken with exceptional cameras and films which would blow people's minds even today in terms of technical resolution. They had their reasons and an equivalent extreme budget. But I could care less if you can scan film at a million DPI. Dots of what ?? Even inkjet machine nozzles tend to clog. What's the point? Seeing a single film grain a meter wide might be interesting in its own right. I had a college background in microscopy. But that has darn little in common with the esthetics of personal printmaking.